Seminar by MSc. Le Tri Dat and BSc. Thai Quynh Mai

On August 04, 2023, the lectures from MSc. Le Tri Dat and BSc. Thai Quynh Mai take place in meeting room B.

MSc. Le Tri Dat presents a talk entitled "Mode shape and frequency of torsional vibration in overhang-shaped cantilevers"

Abstract

The torsional mode of the atomic force microscope (AFM) cantilevers has been widely used in various measurements with high AFM sensitivity. In this study, we conduct a detailed calculation of the frequency and mode shape of the overhang-varying cantilevers in the case of torsional oscillation. The frequency and mode shape of any higher-order mode could be obtained. The change in the mode shape and frequency has been clearly presented where the mode shape presents several maxima for increasing overhang length. This gives a fruitful method for the experimentalist to choose the suitable geometric parameters for the cantilever targeting a specific frequency.

BSc. Thai Quynh Mai presents a talk entitled "Nanoparticles in relation to the amyloid peptide aggregation process" - a review from Zaman et al published on Int J Nanomedicine.

Abstract

Nanoparticles are today very common in nature and as functional ingredients in cosmetic products as well as in medicine. The nucleation and aggregation process of peptides can be significantly affected by nanoparticles. Moreover, the pathogenesis of Alzheimer's disease (AD) progression is implicated to the aggregation of peptides into amyloid fibrils, leading to the formation of toxic Aβ oligomers. Therefore, in this work, the various effects that nanoparticles have on the amyloid peptide aggregation process were investigated using molecular dynamics simulations. The results observed will potentially enhance AD therapy.